The manufacturer’s Co-Pay Card, Medicare’s negotiated price, the new $2,100 out-of-pocket cap, patient assistance for those with no insurance, discount cards, and what changed this year β everything in one place, written for patients, not insurance professionals.
Historic changes took effect this year for Eliquis on Medicare: the 30-year-old “donut hole” coverage gap was permanently eliminated as of 2025 and does not return. The Medicare Part D out-of-pocket cap is now $2,100 per calendar year β once you hit that amount, all your covered Part D drugs cost you nothing for the rest of the year. And Eliquis’s Medicare Maximum Fair Price dropped from $521 to $231 per month β a 56% cut β the first time in U.S. history that Medicare negotiated a drug price directly. If you’re on Medicare and haven’t called your plan to understand what you’ll actually pay at the counter in 2026, that phone call is worth making today. Your plan tier and coinsurance structure determine your real cost, which may be significantly lower than before.
Eliquis (apixaban) carries the FDA’s most serious warning β a Black Box Warning β specifically about stopping it abruptly. Discontinuing Eliquis without medical guidance sharply increases your risk of stroke and life-threatening blood clots. This risk appears quickly β sometimes within days of stopping. If the cost of Eliquis is making you skip doses or consider stopping, call your doctor or pharmacist today β not next week. Every program on this page exists precisely for this reason. Financial help is real and available. Cost alone should never drive this decision. This guide is informational only and does not replace medical or financial advice from a licensed professional.
Three types of patients, three very different routes. Find your column β then jump to that section below.
More than 15 million Americans take Eliquis daily. Without help, it costs around $606 per month. But every patient should know at least one of these programs exists for their situation.
-
1
Can I really get Eliquis for $10 a month? Yes β for commercially insured patients only Β· $10 per 30-day supply via the BMS/Pfizer Co-Pay Card Β· Not for Medicare, Medicaid, VA, or TRICARE patientsBristol-Myers Squibb and Pfizer run the Co-Pay Card program for patients with commercial health insurance β meaning employer coverage, ACA marketplace plans, or privately purchased insurance. When you present an activated card at a participating pharmacy with a valid prescription, your out-of-pocket cost drops to as little as $10 for a 30-day supply, or $10 for your first 90-day fill. Subsequent 90-day refills run $30. The program covers up to 24 months from activation with a maximum annual benefit of $2,000. The card must be activated before its first use β this takes about 10 minutes online or by phone. Five out of ten patients enrolled in this program pay $10 or less per month. The reason federal program patients are excluded: federal law prohibits drug manufacturers from subsidizing costs for government-funded health programs. Activation must occur before December 31, 2026.
-
2
Is Eliquis going to be free in Medicare β what actually changed? Not free β but significantly cheaper Β· Medicare’s new negotiated Maximum Fair Price is $231/month (down from $521) Β· Plus: $2,100 annual out-of-pocket cap on all covered Part D drugs Β· Plus: donut hole permanently eliminated since 2025Three major changes hit simultaneously and they work together. First: Eliquis’s Medicare Maximum Fair Price became $231 per 30-day supply as of January 1, 2026 β a 56% reduction from the $521 list price. This is the price your Medicare Part D plan pays for the drug. Second: the Medicare Part D out-of-pocket cap is $2,100 for the full calendar year. Once your combined deductibles, copays, and coinsurance on covered drugs reach $2,100, all covered Part D drugs β including Eliquis β cost you nothing for the rest of the year. Third: the infamous donut hole coverage gap was permanently eliminated as of 2025. The benefit now has just three phases: your annual deductible, an initial coverage phase (roughly 25% coinsurance), and catastrophic coverage at zero cost. What you actually pay at the pharmacy counter still depends on your specific plan’s formulary tier and copay structure β call your plan directly or visit medicare.gov to see your plan’s current Eliquis cost.
-
3
How do I get a free 30-day trial of Eliquis? Available to all patients who have NEVER previously filled an Eliquis prescription Β· No insurance required Β· Up to 74 tablets at zero cost Β· One use per lifetime Β· Activation must happen before Dec 31, 2026The Free 30-Day Trial Offer works for first-time Eliquis patients regardless of insurance status β including Medicare patients, who are otherwise excluded from the Co-Pay Card. To qualify: you must never have previously filled an Eliquis prescription anywhere; you must have a valid prescription written for 30 days or less (not a 90-day supply); and your treatment must be planned for more than 35 days by your doctor. Ask your prescribing physician for a Free 30-Day Trial card at the same appointment where they write your first prescription. You can also request one at eliquis.bmscustomerconnect.com or call 855-354-7847. Bring the activated card to a participating pharmacy. This offer cannot be combined with the Co-Pay Card β but it is the smart way to start: get the free first month, then immediately enroll in the Co-Pay Card if you have commercial insurance so the $10/month kicks in on your very next fill.
-
4
What is the Medicare Prescription Payment Plan and should I enroll? New option: spread your $2,100 annual OOP costs across 12 monthly installments instead of paying large amounts at the pharmacy Β· No interest Β· No fees Β· No credit check Β· VoluntaryFor Medicare patients who take multiple expensive medications, the beginning of the year can bring large pharmacy bills β you pay your annual deductible and initial coverage costs upfront before the $2,100 cap kicks in. The Medicare Prescription Payment Plan, available starting in 2025 and continuing in 2026, lets you spread those costs across monthly installments billed by your plan instead of paying all at once at the pharmacy counter. There is no interest, no fees, and no credit check. This doesn’t reduce the total you pay β it just makes the cash flow more predictable and manageable. It is particularly helpful for patients on Eliquis plus other expensive medications who might otherwise face a large bill in January or February. Ask your Medicare Part D plan about enrolling, or visit medicare.gov for details. If you also qualify for Medicare Extra Help (Low-Income Subsidy), Extra Help is likely a better deal β it reduces the total amount you pay, not just when you pay it.
-
5
What if I have no insurance and can’t afford Eliquis at all? BMSPAF may provide free Eliquis Β· Call 800-736-0003 or apply at bmspaf.org Β· Income generally under 300% federal poverty level Β· No insurance required Β· Also: 40%+ off via Eliquis 360 Support direct-to-patient (~$346/mo)Two options exist specifically for uninsured and underinsured patients. The Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) is an independent nonprofit that may provide Eliquis completely free. Requirements: U.S. resident, uninsured or underinsured, financial hardship with household income generally at or below 300% of the federal poverty level, and a valid prescription. Applying is free. If you have Medicare, you must first demonstrate that you do not qualify for Extra Help (the Low-Income Subsidy) before BMSPAF will consider your application. The second option is Eliquis 360 Support’s direct-to-patient program, which ships Eliquis directly to your home at over 40% below the current list price β bringing the effective cost to approximately $346 per month. This requires no insurance and is available in all 50 states and Puerto Rico. Call 855-354-7847 or visit the 360 Support page at eliquis.bmscustomerconnect.com to explore both options. Don’t wait until you’ve run out of medication to apply for BMSPAF β processing takes time.
-
6
Can I use GoodRx or SingleCare to lower Eliquis costs? Yes β but they’re a cash-price alternative, not an add-on to insurance Β· Brand Eliquis: ~$300β$450/mo via discount cards Β· SingleCare: as low as ~$156 for 28 tablets (5 mg) Β· Cannot be used with insurance simultaneouslyPrescription discount platforms like GoodRx, SingleCare, and Mark Cuban’s Cost Plus Drugs negotiate cash prices with pharmacies and are most useful when your insurance copay exceeds the discount card price. They cannot be used alongside your insurance at the same fill β it is one or the other per transaction. For brand Eliquis without insurance, GoodRx typically brings the cost to $300β$450 per month depending on the pharmacy; SingleCare has shown prices as low as $156 for a 28-tablet supply of 5 mg tablets. Prices vary dramatically between pharmacies in the same city β always compare across at least two locations using GoodRx or SingleCare before filling. Important: prescription discount cards cannot be used with the manufacturer’s Co-Pay Card either. Pick the lowest-cost path for each fill and stick with it. Prices update regularly, so check before every fill rather than assuming last month’s best price still applies.
-
7
Is a generic version of Eliquis available right now? Not widely available yet β broad generic launch expected April 2028 Β· Individual pharmacies may have limited supply from early-entry settlement manufacturers Β· Generic apixaban ~$25β$60/mo via discount cards if available at your pharmacyGeneric apixaban (the active ingredient in Eliquis) has a complicated history in the U.S. The FDA approved multiple generic manufacturers beginning in 2019, but patent protections held by the BMS-Pfizer Alliance blocked them from the market. Settlement agreements established April 1, 2028 as the broad market entry date, though some manufacturers reached separate early-entry settlement agreements allowing limited supply before that date. If your pharmacist currently has generic apixaban in stock and your doctor has not written “Dispense as Written” on the prescription, you can ask to fill with the generic β through discount cards, prices run around $25β$60 per month. Generic apixaban contains the identical active ingredient in the same dose and must meet FDA bioequivalence standards. That said, always confirm any switch from brand to generic with your prescribing physician first, particularly for blood thinners where consistency of therapy is clinically important.
-
8
What is Medicare Extra Help and how does it affect what I pay for Eliquis? Extra Help (Low-Income Subsidy) caps copays as low as zero for qualifying Medicare Part D enrollees Β· Apply free at ssa.gov/extrahelp Β· Call Social Security: 1-800-772-1213 Β· Expanded eligibility since 2024 β more seniors qualify nowMedicare Extra Help β formally the Low-Income Subsidy (LIS) β is a federal program administered through Social Security that reduces prescription drug costs for Medicare Part D enrollees with limited income and resources. For full Extra Help recipients in 2026, the maximum copay for covered drugs including Eliquis is $12.65 per fill up to the $2,100 out-of-pocket threshold β and $0 once you’re above that threshold. The Inflation Reduction Act of 2022 expanded the income eligibility threshold for full Extra Help benefits starting in 2024, bringing more seniors into coverage who previously received partial help or none. If you qualify for both Medicaid and Medicare (dual eligible), you are automatically enrolled in Extra Help at no cost. To apply: visit ssa.gov/extrahelp, call Social Security at 1-800-772-1213, or get free help through your local SHIP counselor at shiphelp.org. The application is free and can be submitted any time of year. BMSPAF’s patient assistance program requires you to first check your Extra Help eligibility β so this is a step you should take before applying to BMSPAF anyway.
The past 18 months brought more changes to Eliquis affordability than the previous decade combined. Here’s what every patient should know right now.
If you have commercial (private) insurance, this is the fastest path to $10 Eliquis. The whole process takes about 10 minutes.
-
1
Confirm you have commercial insurance. Look at your insurance card. If it says a plan name like Blue Cross, Aetna, Cigna, UnitedHealthcare, or your employer’s plan β you qualify. If it says Medicare, Medicaid, Medigap, VA, or TRICARE β you do not qualify for the Co-Pay Card. Medicare patients should jump to the Medicare section and the Extra Help information instead.
-
2
Get a valid Eliquis prescription from your doctor. Any current valid prescription works. If you’re already taking Eliquis, your existing prescription is fine. If you’re just starting, your doctor will write one at your appointment.
-
3
Enroll and activate your card β online or by phone. Visit eliquis.bmscustomerconnect.com/savings or call 1-855-ELIQUIS (354-7847) MondayβFriday 8 AMβ8 PM ET, SaturdayβSunday 9 AMβ6 PM ET. You can receive your activated card by email, text, or mail. Have your prescription and insurance information ready. The card must be activated before you use it for the first time.
-
4
Present the activated card at a participating pharmacy with your prescription. Most major retail pharmacies in the U.S. participate. If you use mail-order or a non-participating pharmacy, call 866-279-4730 for a patient rebate form, or go to patientrebateonline.com to get reimbursed after paying out of pocket.
-
5
Know your annual limit and re-enroll when needed. The card covers up to 24 months from activation with a maximum annual benefit of $2,000. When your card reaches 24 months, you can re-enroll if you remain eligible. If you hit the $2,000 annual cap before year-end, you’ll pay your plan’s standard copay until the new calendar year starts. Note: the offer is not applicable if your copay is already $10 or less.
Use these buttons to find pharmacies, Medicare counselors, and patient assistance resources near your current location.
- Step 1 β Identify your insurance type first. Check your insurance card. Commercial plan name (Blue Cross, Aetna, Cigna, employer plan) = you’re likely eligible for the $10 Co-Pay Card. Medicare, Medicaid, VA, or TRICARE = Co-Pay Card is not for you. Jump to Step 3 instead.
- Step 2 β Commercial insurance? Enroll in the Co-Pay Card today. Call 1-855-ELIQUIS (354-7847) or visit eliquis.bmscustomerconnect.com/savings. Activation must occur before December 31, 2026. The process takes about 10 minutes and the savings are immediate at your next fill.
- Step 3 β On Medicare? Call your plan and ask exactly what you’ll pay in 2026. The new $231 Maximum Fair Price lowers the baseline, but your actual copay depends on your plan’s formulary tier. Ask specifically: Is Eliquis on my formulary? What tier is it? Is prior authorization required? Then check whether you qualify for Extra Help at ssa.gov/extrahelp β it could reduce your costs to as little as $12.65 per fill.
- Step 4 β Uninsured or underinsured? Apply to BMSPAF now β before you run low. Visit bmspaf.org or call 800-736-0003. The application is free. Gather income proof, your prescription, and insurance documentation. If you don’t qualify for full assistance, the Eliquis 360 Support direct-to-patient program provides 40%+ off delivery to your door at roughly $346/month β no insurance needed.
- Step 5 β Compare pharmacy prices before every single fill. The same medication costs meaningfully different amounts at different pharmacies in the same city. Check GoodRx.com and SingleCare.com before you fill. If generic apixaban is available at your pharmacy and your doctor approves it, the discount card price for the generic is often $25β$60 per month β the most affordable option currently available.
π Key Contacts & Resources:
π³ Co-Pay Card: eliquis.bmscustomerconnect.com π Eliquis Support: 1-855-ELIQUIS (354-7847) π€ Free Medication: bmspaf.org Β· 800-736-0003 π¦ 40% Off Direct: eliquis 360 Support line π Discount Cards: goodrx.com Β· singlecare.com π§ββοΈ Mark Cuban Pharmacy: costplusdrugs.com π΅ Medicare Help: medicare.gov Β· 1-800-MEDICARE π€ Medicare Extra Help: ssa.gov/extrahelp Β· 1-800-772-1213 π Free Medicare Counseling: shiphelp.org π Find More PAPs: needymeds.org Β· rxassist.org π¬ Mail Rebate: patientrebateonline.com ποΈ Medicare Patient Rights: medicarerights.org Β· 800-333-4114 π Verify Online Pharmacies: nabp.pharmacy/consumers β οΈ Report Counterfeits: fda.gov/safety/medwatchThis guide is for informational purposes only. It is not medical advice, financial advice, or legal advice. Eligibility for any savings program is determined solely by the program administrator and is subject to change without notice. Program terms, prices, income limits, and availability are based on publicly available information and manufacturer disclosures current as of July 2026 β verify all details directly at eliquis.bmscustomerconnect.com, bmspaf.org, and medicare.gov before acting. Never stop taking a blood thinner without guidance from your prescribing physician. If you believe you are experiencing a stroke or blood clot, call 911 or go to an emergency room immediately. For questions about Medicare Part D coverage, call 1-800-MEDICARE (1-800-633-4227).